TargetMol

CDK ligand for PROTAC hydrochloride

Product Code:
 
TAR-T10734L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10734L-200mg200mgEnquire
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TAR-T10734L-500mg500mgEnquire
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TAR-T10734L-5mg5mg£320.00
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TAR-T10734L-1mL1 mL * 10 mM (in DMSO)£361.00
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TAR-T10734L-10mg10mg£461.00
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TAR-T10734L-25mg25mg£772.00
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TAR-T10734L-50mg50mg£1,238.00
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TAR-T10734L-100mg100mg£1,662.00
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Further Information

Bioactivity:
CDK ligand for PROTAC hydrochloride is a CDK inhibitor with antitumor activity. It has been used to design PROTAC CDK4/6 degraders.
CAS:
T10734L
Formula:
C25H29ClF2N8O
Molecular Weight:
531
Purity:
0.98
SMILES:
FC(C=N1)=C(C2=CC(N(C(C)C)C(CO)=N3)=C3C(F)=C2)N=C1NC4=NC=C(C=C4)CN5CCNCC5.[H]Cl

References

1. Nathanael Gray, et al. Degradation of cyclin-dependent kinase 4/6 (cdk4/6) by conjugation of cdk4/6 inhibitors with e3 ligase ligand and methods of use. WO2017185031A1.