TargetMol

Closthioamide

Product Code:
 
TAR-T10838
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10838-5mg5mg£930.00
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TAR-T10838-50mg50mg£1,821.00
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Quantity:
TAR-T10838-100mg100mg£2,319.00
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This product comes from: United States.
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Further Information

Bioactivity:
Closthioamide is a potent inhibitor of bacterial DNA gyrase and highly active against MRSA, Ec, VRE, and Mv (MICs: 0.58 μM, 9.00 μM, 0.58 μM and 72.03 μM).
CAS:
1227367-59-0
Formula:
C29H38N6O2S6
Molecular Weight:
695.02
Pathway:
Microbiology/Virology
Purity:
0.98
SMILES:
Oc1ccc(cc1)C(=S)NCCC(=S)NCCC(=S)NCCCNC(=S)CCNC(=S)CCNC(=S)c1ccc(O)cc1
Target:
Antibacterial

References

1. Chiriac AI, et al. Mode of action of closthioamide: the first member of the polythioamide class of bacterial DNA gyrase inhibitors. J AntimicrobChemother. 2015Sep;70(9):2576-88. 2. Lincke T, et al. Closthioamide: an unprecedented polythioamide antibiotic from the strictly anaerobic bacterium Clostridium cellulolyticum.Angew Chem Int Ed Engl. 2010 Mar 8;49(11):2011-3.