TargetMol

CUDA

Product Code:
 
TAR-T10900
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10900-5mg5mg£103.00
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Quantity:
TAR-T10900-1mL1 mL * 10 mM (in DMSO)£107.00
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TAR-T10900-10mg10mg£124.00
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TAR-T10900-25mg25mg£177.00
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TAR-T10900-50mg50mg£246.00
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Quantity:
TAR-T10900-100mg100mg£353.00
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Further Information

Bioactivity:
CUDA is an effective soluble cyclohydrolase inhibitor with IC50 of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively. CUDA selectively increases the activity of peroxisome proliferator-activated receptor (PPAR) alpha. CUDA may be valuable for the study of cardiovascular diseases.
CAS:
479413-68-8
Formula:
C19H36N2O3
Molecular Weight:
340.508
Pathway:
DNA Damage/DNA Repair; Metabolism
Purity:
0.98
SMILES:
OC(=O)CCCCCCCCCCCNC(=O)NC1CCCCC1
Target:
PPAR; Epoxide Hydrolase

References

1. Morisseau C, et al. Structural refinement of inhibitors of urea-based soluble epoxide hydrolases. Biochem Pharmacol. 2002 May 1;63(9):1599-608. 2. Fang X, et al. Activation of peroxisome proliferator-activated receptor alpha by substituted urea-derived soluble epoxide hydrolase inhibitors. J Pharmacol Exp Ther. 2005 Jul;314(1):260-70.