TargetMol

EC0488

Product Code:
 
TAR-T11144
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11144-5mg5mg£850.00
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Further Information

Bioactivity:
EC0488 was used to synthesize EC0531, which has folic acid receptor specificity and anti-tumor activity.
CAS:
1059477-92-7
Formula:
C65H98N16O34S
Molecular Weight:
1679.64
Purity:
0.98
SMILES:
Nc1nc2[nH]cc(CNc3ccc(cc3)C(=O)N[C@@H](CCC(=O)N[C@@H](CCC(=O)NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(=O)NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(=O)NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)C(=O)N[C@@H](CS)C(O)=O)C(O)=O)nc2c(=O)n1

References

1. Leamon CP, et al. Enhancing the therapeutic range of a targeted small-molecule tubulysin conjugate for folate receptor-based cancer therapy. Cancer Chemother Pharmacol. 2017 Jun;79(6):1151-1160.