TargetMol

GFB-8438

Product Code:
 
TAR-T11394
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11394-1mg1mg£103.00
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TAR-T11394-2mg2mg£118.00
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TAR-T11394-1mL1 mL * 10 mM (in DMSO)£148.00
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TAR-T11394-5mg5mg£148.00
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TAR-T11394-10mg10mg£195.00
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TAR-T11394-25mg25mg£274.00
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TAR-T11394-50mg50mg£356.00
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TAR-T11394-100mg100mg£495.00
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Further Information

Bioactivity:
GFB-8438 is a potent and subtype selective inhibitor of TRPC5(IC50s of 0.18 and 0.29 μM of hTRPC5 and hTRPC4, respectively).
CAS:
2304549-73-1
Formula:
C16H14ClF3N4O2
Molecular Weight:
386.76
Pathway:
Membrane transporter/Ion channel
Purity:
0.9929
SMILES:
FC(F)(F)c1ccccc1CN1CCN(CC1=O)c1cn[nH]c(=O)c1Cl
Target:
TRP/TRPV Channel

References

1. Yu M, et al.Discovery?of a?Potent?and?Selective?TRPC5?Inhibitor,?Efficacious?in a?Focal?Segmental?Glomerulosclerosis?Model.ACS Med Chem Lett.?2019 Oct 22;10(11):1579-1585.