TargetMol

GNE-8505

Product Code:
 
TAR-T11440
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11440-5mg5mg£270.00
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Quantity:
TAR-T11440-50mg50mg£1,018.00
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Quantity:
TAR-T11440-100mg100mg£1,508.00
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This product comes from: United States.
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Further Information

Bioactivity:
GNE-8505 is an orally available inhibitor of Dual leucine zipper kinase (DLK).
CAS:
1620573-48-9
Formula:
C21H24F3N5O
Molecular Weight:
419.452
Pathway:
DNA Damage/DNA Repair
Purity:
0.98
SMILES:
[H][C@@]12CN(C[C@]1([H])[C@H]2c1cc(nn1CC1CC1)-c1cnc(N)c(c1)C(F)(F)F)C1COC1
Target:
DNA Alkylation

References

1. Le Pichon CE, et al. Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease. Sci Transl Med. 2017 Aug 16;9(403). pii: eaag0394.