TargetMol

Phenoxybenzamine

Product Code:
 
TAR-T1158L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-T1158L-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Bioactivity:
Phenoxybenzamine is an α-1 adrenergic receptor antagonist. Phenoxybenzamine may exert a neuroprotective effect by reducing neuroinflammation after traumatic brain injury.
CAS:
59-96-1
Formula:
C18H22ClNO
Molecular Weight:
303.83
Purity:
0.98
SMILES:
CC(N(CCCl)CC1=CC=CC=C1)COC2=CC=CC=C2

References

1. van der Zee PA, de Boer A. Pheochromocytoma: a review on preoperative treatment with phenoxybenzamine or doxazosin. Neth J Med. 2014 May;72(4):190-201. Review. PubMed PMID: 24829175. 2. National Toxicology Program. Phenoxybenzamine hydrochloride. Rep Carcinog. 2011;12:344-5. PubMed PMID: 21863081. 3. Rau TF, Kothiwal A, Rova A, Rhoderick JF, Poulsen DJ. Phenoxybenzamine is neuroprotective in a rat model of severe traumatic brain injury. Int J Mol Sci. 2014 Jan 20;15(1):1402-17. doi: 10.3390/ijms15011402. PubMed PMID: 24447929; PubMed Central PMCID: PMC3907876. 4. Lin XB, Jiang L, Ding MH, Chen ZH, Bao Y, Chen Y, Sun W, Zhang CR, Hu HK, Cai Z, Lu CY, Zhou JY, Qian J, Wu XJ, Jin WL, Hu GH. Anti-tumor activity of phenoxybenzamine hydrochloride on malignant glioma cells. Tumour Biol. 2016 Mar;37(3):2901-8. doi: 10.1007/s13277-015-4102-y. Epub 2015 Sep 26. PubMed PMID: 26409450.