TargetMol

IACS-8803

Product Code:
 
TAR-T11596
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T11596-5mg5mg£850.00
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TAR-T11596-50mg50mg£1,661.00
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TAR-T11596-100mg100mg£2,079.00
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Further Information

Bioactivity:
IACS-8803 is a highly potent cyclic dinucleotide STING agonist with robust systemic antitumor efficacy.
CAS:
2095690-70-1
Formula:
C20H23FN10O9P2S2
Molecular Weight:
692.53
Purity:
0.98
SMILES:
Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]2CO[P@](S)(=O)O[C@@H]3[C@H](O)[C@@H](CO[P@](S)(=O)O[C@H]2[C@H]1F)O[C@H]3n1cnc2c(N)ncnc12

References

1. Ager CR, et al. Discovery of IACS-8803 and IACS-8779, potent agonists of stimulator of interferon genes (STING) with robust systemic antitumor efficacy. Bioorg Med Chem Lett. 2019 Oct 15;29(20):126640.