TargetMol

IDH1 Inhibitor 3

Product Code:
 
TAR-T11612
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11612-5mg5mg£1,171.00
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TAR-T11612-50mg50mg£2,303.00
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Quantity:
TAR-T11612-100mg100mg£3,042.00
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This product comes from: United States.
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Further Information

Bioactivity:
IDH1 Inhibitor 3 is a mutant isocitric dehydrogenase 1 (IDH1) inhibitor (IC50: 45 nM for IDH1R132H).
CAS:
2171081-24-4
Formula:
C31H25F4N5O3
Molecular Weight:
591.567
Purity:
0.98
SMILES:
Fc1cc(F)cc(c1)N(C(=O)[C@H]1CCC(=O)N1c1cc(ccn1)C#N)[C@]1(CCc2ccccc12)C(=O)NC1CC(F)(F)C1

References

1. Qiangang Zheng, et al. Discovery and structure-activity-relationship study of novel conformationally restricted indane analogues for mutant isocitric dehydrogenase 1 (IDH1) inhibitors. Bioorganic & Medicinal Chemistry Letters 27 (2017) 5262-5266.