TargetMol

Isoguvacine hydrochloride

Product Code:
 
TAR-T11684
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11684-25mg25mg£118.00
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TAR-T11684-50mg50mg£148.00
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TAR-T11684-100mg100mg£189.00
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TAR-T11684-500mg500mg£378.00
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Further Information

Bioactivity:
Isoguvacine hydrochloride is a GABA receptor agonist. Isoguvacine hydrochloride binds to rat synaptic cortical membranes and activates α1β2γ2S, α2β2γ2S, α3β2γ2S, α5β2γ2S, and ?1 subunit GABAA receptors.
CAS:
68547-97-7
Formula:
C6H10ClNO2
Molecular Weight:
163.6
Pathway:
Neuroscience; Membrane transporter/Ion channel
Purity:
0.9941
SMILES:
Cl.OC(=O)C1=CCNCC1
Target:
GABA Receptor

References

1. White WF, et al. Isoguvacine binding, uptake, and release: relation to the GABA system. J Neurochem. 1983 Jun;40(6):1701-8. 2. Wahab A, et al. Effects of gamma-aminobutyric acid (GABA) agonists and a GABA uptake inhibitor on pharmacoresistant seizure like events in organotypic hippocampal slice cultures. Epilepsy Res. 2009 Oct;86(2-3):113-23. 3. Morin AM, et al. The binding of 3H-isoguvacine to mouse brain synapticmembranes. Life Sci. 1980 Apr 14;26(15):1239-45.