TargetMol

JAK-IN-1

Product Code:
 
TAR-T11703
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11703-5mg5mg£703.00
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Quantity:
TAR-T11703-50mg50mg£1,982.00
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Quantity:
TAR-T11703-100mg100mg£2,560.00
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This product comes from: United States.
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Further Information

Bioactivity:
JAK-IN-1 shows improved selectivity for JAK3 over JAK1. JAK-IN-1 is a JAK1/2/3 inhibitor with IC50s of 0.26, 0.8 and 3.2 nM, respectively.
CAS:
1334673-53-8
Formula:
C20H24N6O2
Molecular Weight:
380.452
Purity:
0.98
SMILES:
CC(C)(C)[C@@H](NC(=O)c1c[nH]c2ncc(nc12)C1CC1)C(=O)N1CC(C1)C#N

References

1. Soth M, et al. 3-Amido pyrrolopyrazine JAK kinase inhibitors: development of a JAK3 vs JAK1 selective inhibitor and evaluation in cellular and in vivo models. J Med Chem. 2013 Jan 10;56(1):345-56.