TargetMol

JAK-IN-4

Product Code:
 
TAR-T11705
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11705-5mg5mg£1,171.00
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Quantity:
TAR-T11705-50mg50mg£2,303.00
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Quantity:
TAR-T11705-100mg100mg£3,042.00
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This product comes from: United States.
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Further Information

Bioactivity:
JAK-IN-4 is a prodrug of a JAK inhibitor, effective in murine collagen induced arthritis model.
CAS:
1400877-37-3
Formula:
C18H19N4Na2O6P
Molecular Weight:
464.325
Purity:
0.98
SMILES:
C[C@@H](O)[C@@H](COP(=O)(O[Na])O[Na])Nc1c(cnn2cc(cc12)-c1ccccc1)C(N)=O

References

1. Spergel SH, et al. Discovery of a JAK1/3 Inhibitor and Use of a Prodrug To Demonstrate Efficacy in a Model of Rheumatoid Arthritis. ACS Med Chem Lett. 2019 Feb 13;10(3):306-311.