TargetMol

KRN2

Product Code:
 
TAR-T11781
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11781-5mg5mg£850.00
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Quantity:
TAR-T11781-50mg50mg£1,661.00
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Quantity:
TAR-T11781-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
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Further Information

Bioactivity:
KRN2 has potential to treat NFAT5-mediated Chronic Arthritis. KRN2 is a selective inhibitor of nuclear factor of activated T cells (NFAT5), with an IC50 of 100 nM.
CAS:
248260-75-5
Formula:
C27H23ClFNO4
Molecular Weight:
479.93
Purity:
0.98
SMILES:
[Cl-].COc1ccc2c(Cc3ccccc3F)c3-c4cc5OCOc5cc4CC[n+]3cc2c1OC

References

1. Han EJ, et al. Suppression of NFAT5-mediated Inflammation and Chronic Arthritis by Novel ?B-binding Inhibitors. EBioMedicine. 2017 Apr;18:261-273.