TargetMol

L791943

Product Code:
 
TAR-T11810
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11810-5mg5mg£1,091.00
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TAR-T11810-50mg50mg£2,143.00
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Quantity:
TAR-T11810-100mg100mg£2,801.00
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This product comes from: United States.
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Further Information

Bioactivity:
L791943 is a selective, potent) inhibitor of Phosphodiesterase-4 (PDE4,IC50 of 4.2 nM).
CAS:
192767-01-4
Formula:
C24H17F10NO4
Molecular Weight:
573.387
Purity:
0.98
SMILES:
OC(c1ccc(cc1)C(Cc1ccn(=O)cc1)c1ccc(OC(F)F)c(OC(F)F)c1)(C(F)(F)F)C(F)(F)F

References

1. Richard Frenette, et al. Substituted 4-(2,2-diphenylethyl)pyridine-N-oxides as phosphodiesterase-4 inhibitors: SAR study directed toward the improvement of pharmacokinetic parameters. Bioorg Med Chem Lett. 2002 Oct 21;12(20):3009-13. 2. Guay D, et al. Discovery of L-791,943: a potent, selective, non emetic and orally active phosphodiesterase-4 inhibitor. Bioorg Med Chem Lett. 2002 Jun 3;12(11):1457-61.