TargetMol

LCH-7749944

Product Code:
 
TAR-T11826
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11826-1mg1mg£137.00
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TAR-T11826-5mg5mg£229.00
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TAR-T11826-1mL1 mL * 10 mM (in DMSO)£249.00
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TAR-T11826-10mg10mg£326.00
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TAR-T11826-25mg25mg£499.00
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TAR-T11826-50mg50mg£687.00
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Quantity:
TAR-T11826-100mg100mg£938.00
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Further Information

Bioactivity:
LCH-7749944 effectively suppresses the proliferation of human gastric cancer cells through downregulation of PAK4/c-Src/EGFR/cyclin D1 pathway and induces apoptosis. LCH-7749944 is a potent PAK4 inhibitor with an IC50 of 14.93 μM.
CAS:
796888-12-5
Formula:
C20H22N4O2
Molecular Weight:
350.422
Pathway:
Cytoskeletal Signaling; Apoptosis
Purity:
0.9928
SMILES:
COc1cccc(Nc2nc(NCC3CCCO3)c3ccccc3n2)c1
Target:
Apoptosis; PAK

References

1. Zhang J, et al. LCH-7749944, a novel and potent p21-activated kinase 4 inhibitor, suppresses proliferation and invasion in human gastric cancer cells. Cancer Lett. 2012 Apr 1;317(1):24-32.