TargetMol

MEN11467

Product Code:
 
TAR-T12000
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12000-5mg5mg£850.00
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Quantity:
TAR-T12000-50mg50mg£1,661.00
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Quantity:
TAR-T12000-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
MEN11467 is a orally- effective and selective peptidomimetic tachykinin NK1 receptor antagonist.
CAS:
214487-46-4
Formula:
C38H40N4O3
Molecular Weight:
600.763
Purity:
0.98
SMILES:
CN([C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H]1CCCC[C@@H]1NC(=O)c1c[nH]c2ccccc12)C(=O)Cc1ccc(C)cc1

References

1. Cirillo R, et al. Pharmacology of MEN 11467: a potent new selective and orally- effective peptidomimetic tachykinin NK(1) receptor antagonist. Neuropeptides. 2001 Jun-Aug;35(3-4):137-47. 2. Khan S, et al. Effect of the long-acting tachykinin NK(1) receptor antagonist MEN 11467 on tracheal mucus secretion in allergic ferrets. Br J Pharmacol. 2001 Jan;132(1):189-96. 3. Palma C, et al. Anti-tumour activity of tachykinin NK1 receptor antagonists on human glioma U373 MG xenograft. Br J Cancer. 2000 Jan;82(2):480-7.