TargetMol

NVS-CRF38

Product Code:
 
TAR-T12276
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12276-5mg5mg£930.00
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TAR-T12276-50mg50mg£1,821.00
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Quantity:
TAR-T12276-100mg100mg£2,319.00
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This product comes from: United States.
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Further Information

Bioactivity:
NVS-CRF38 is an antagonist of corticotropin-releasing factor receptor 1 (CRF1).
CAS:
1207258-55-6
Formula:
C19H21N5O2
Molecular Weight:
351.41
Purity:
0.98
SMILES:
COc1ccc(-c2c(C)oc3c(c(C)nn23)-n2nc(C)nc2C)c(C)c1

References

1. Stringer RA, et al. Preclinical metabolism and pharmacokinetics of NVS-CRF38, a potent and orally bioavailable corticotropin-releasing factor receptor 1 antagonist. Xenobiotica. 2014 Apr 3. 2. Stringer RA, et al. 1-Aminobenzotriazole modulates oral drug pharmacokinetics through cytochrome P450 inhibition and delay of gastric emptying in rats. Drug Metab Dispos. 2014 Jul;42(7):1117-24.