TargetMol

Flumazenil

Product Code:
 
TAR-T1240
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T1240-1mL1 mL * 10 mM (in DMSO)£96.00
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TAR-T1240-10mg10mg£107.00
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TAR-T1240-25mg25mg£130.00
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TAR-T1240-50mg50mg£160.00
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TAR-T1240-100mg100mg£189.00
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Further Information

Bioactivity:
Flumazenil antagonizes the benzodiazepine binding site of the gamma-aminobutyric acid (GABA)/benzodiazepine receptor complex in the central nervous system (CNS), thereby preventing the chloride channel opening events and inhibiting neuronal hyperpolarization. As a result, flumazenil reverses benzodiazepine-induced effects including sedation, psychomotor deficits, amnesia, and hypoventilation in a dose-dependent manner. Flumazenil is an imidazobenzodiazepine derivative, effective in reversing benzodiazepine-induced activities.
CAS:
78755-81-4
Formula:
C15H14FN3O3
Molecular Weight:
303.29
Pathway:
Membrane transporter/Ion channel; Neuroscience
Purity:
0.9991
SMILES:
CCOC(=O)c1ncn-2c1CN(C)C(=O)c1cc(F)ccc-21
Target:
GABA Receptor

References

1. Hoffman EJ, et al. Clin Pharm, 1993, 12(9), 641-656. 2. Belzung C, et al. Psychopharmacology (Berl), 2000, 148(1), 24-32. 3. Fern?ndez-Guasti A, et al. Eur J Pharmacol. 1995 Jul 25;281(1):113-5. 4. L?scher W,et al. Br J Pharmacol. 1994 Dec;113(4):1349-57. 5. Moy SS, et al. Psychopharmacology (Berl), 1997, 131(4), 354-360.