TargetMol

PDK4-IN-1 hydrochloride

Product Code:
 
TAR-T12412L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12412L-1mg1mg£174.00
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TAR-T12412L-5mg5mg£324.00
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TAR-T12412L-1mL1 mL * 10 mM (in DMSO)£349.00
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TAR-T12412L-10mg10mg£458.00
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TAR-T12412L-25mg25mg£704.00
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TAR-T12412L-50mg50mg£938.00
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Quantity:
TAR-T12412L-100mg100mg£1,259.00
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Quantity:
TAR-T12412L-500mg500mg£2,456.00
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This product comes from: United States.
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Further Information

Bioactivity:
PDK4-IN-1 hydrochloride is an anthraquinone derivative and a potent and orally active inhibitor of pyruvate dehydrogenase kinase 4 (PDK4, IC50 value = 84 nM).
CAS:
2310262-11-2
Formula:
C22H20ClN3O2
Molecular Weight:
393.87
Pathway:
Apoptosis; PI3K/Akt/mTOR signaling
Purity:
0.98
SMILES:
Cl.O=C1c2ccccc2C(=O)c2c(cccc12)-c1cnn(c1)C1CCNCC1
Target:
Apoptosis; PDK

References

1. Lee D, et al. Discovery of Novel Pyruvate Dehydrogenase Kinase 4 Inhibitors for Potential Oral Treatment of Metabolic Diseases. J Med Chem. 2019 Jan 24;62(2):575-588.