TargetMol

PF-2771

Product Code:
 
TAR-T12434
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12434-100mg100mg£1,267.00
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Further Information

Bioactivity:
PF-2771 is an inhibitor of centromere protein E (CENP-E)(IC50 of 16.1 nM).
CAS:
T12434
Formula:
C29H36ClN5O4
Molecular Weight:
554.08
Pathway:
Cytoskeletal Signaling
Purity:
0.98
SMILES:
ClC1=CC(C(N[C@@H](CC2=CC=C(C3=CN(C)C(C(C)=O)=N3)C=C2)CNC(CN(C)C)=O)=O)=CC=C1OC(C)C
Target:
Kinesin

References

1. Kung PP, et al. Chemogenetic evaluation of the mitotic kinesin CENP-E reveals a critical role in triple-negative breast cancer. Mol Cancer Ther. 2014 Aug;13(8):2104-15.