TargetMol

PI3Kγ inhibitor 2

Product Code:
 
TAR-T12465
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12465-5mg5mg£1,010.00
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TAR-T12465-50mg50mg£1,982.00
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Quantity:
TAR-T12465-100mg100mg£2,560.00
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This product comes from: United States.
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Further Information

Bioactivity:
PI3Kγ inhibitor 2 is an orally bioavailable inhibitor of PI3Kγ(Ki of 4 nM).
CAS:
1315538-79-4
Formula:
C20H18F3N5O3
Molecular Weight:
433.391
Pathway:
PI3K/Akt/mTOR signaling
Purity:
0.98
SMILES:
COc1cc(cnc1OC)-c1ccc2C(=O)N([C@H](C)c2n1)c1cnn(CC(F)(F)F)c1
Target:
PI3K

References

1. Come JH, et al. Design and Synthesis of a Novel Series of Orally Bioavailable, CNS-Penetrant, Isoform Selective Phosphoinositide 3-Kinase ? (PI3K?) Inhibitors with Potential for the Treatment of Multiple Sclerosis (MS). J Med Chem. 2018 Jun 28;61(12):5245-5256.