TargetMol

Pitolisant oxalate

Product Code:
 
TAR-T12491
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12491-5mg5mg£850.00
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TAR-T12491-50mg50mg£1,661.00
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Quantity:
TAR-T12491-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Pitolisant oxalate is a potent and selective inverse agonist of nonimidazole at the recombinant human histamine H3 receptor with Ki of 0.16 nM.
CAS:
362665-57-4
Formula:
C19H28ClNO5
Molecular Weight:
385.89
Purity:
0.98
SMILES:
OC(=O)C(O)=O.Clc1ccc(CCCOCCCN2CCCCC2)cc1

References

1. Ligneau X, et al. BF2.649 [1-{3-[3-(4-Chlorophenyl)propoxy]propyl}piperidine, hydrochloride], a nonimidazole inverse agonist/antagonist at the human histamine H3 receptor: Preclinical pharmacology. J Pharmacol Exp Ther. 2007 Jan;320(1):365-75. 2. Dudek M, et al. H3 histamine receptor antagonist pitolisant reverses some subchronic disturbances induced by olanzapine in mice. Metab Brain Dis. 2016 Oct;31(5):1023-9. 3. Uguen M, et al. Preclinical evaluation of the abuse potential of Pitolisant, a histamine H? receptor inverse agonist/antagonist compared with Modafinil. Br J Pharmacol. 2013 Jun;169(3):632-44.