TargetMol

PROTAC B-Raf degrader 1

Product Code:
 
TAR-T12556
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T12556-100mg100mgEnquire
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TAR-T12556-5mg5mg£417.00
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TAR-T12556-10mg10mg£624.00
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Further Information

Bioactivity:
PROTAC B-Raf degrader 1 is a proteolysis targeting chimera (PROTAC) for the degradation of B-Raf,PROTAC B-Raf degrader 1 With anti-cancer activity.
CAS:
2364367-27-9
Formula:
C36H37N5O12S
Molecular Weight:
763.78
Pathway:
MAPK
Purity:
0.98
SMILES:
COc1cc(OC)c(C=CS(=O)(=O)Cc2ccc(OC)c(NCC(=O)NCC(=O)Nc3cccc4C(=O)N(C5CCC(=O)NC5=O)C(=O)c34)c2)c(OC)c1
Target:
Raf

References

1. Chen H, et al. Pomalidomide hybrids act as proteolysis targeting chimeras: Synthesis, anticancer activity and B-Raf degradation. Bioorg Chem. 2019 Mar 19;87:191-199.