TargetMol

PrPSc-IN-1

Product Code:
 
TAR-T12563
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12563-5mg5mg£850.00
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Further Information

Bioactivity:
PrPSc-IN-1 is a fluorescent probe, binds to the misfolded protein PrPSc, inhibits its accumulation(IC50 of 1.6 μM), with anti-prion activity.
CAS:
1315475-30-9
Formula:
C22H17N5O
Molecular Weight:
367.412
Purity:
0.98
SMILES:
COc1ccc2c(c1)nc(NN=Cc1ccnc3ccccc13)c1cccn21

References

1. Zaccagnini L, et al. Identification of novel fluorescent probes preventing PrPSc replication in prion diseases. Eur J Med Chem. 2017 Feb 15;127:859-873.