TargetMol

R916562

Product Code:
 
TAR-T12650
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12650-5mg5mg£850.00
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Quantity:
TAR-T12650-50mg50mg£1,661.00
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Quantity:
TAR-T12650-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
R916562 is an orally active and selective Axl/VEGF-R2 inhibitor with IC50s of 136 nM and 24 nM, respectively. R916562 has anti-angiogenesis and anti-metastasis.
CAS:
1037798-41-6
Formula:
C26H30ClN9S
Molecular Weight:
536.1
Pathway:
Tyrosine Kinase/Adaptors
Purity:
0.98
SMILES:
Cc1csc2c(nc(Cl)nc12)-n1nc(Nc2ccc(cc2)N2CCN(CC2)[C@@H]2C[C@H]3CC[C@@H]2C3)nc1N
Target:
TAM Receptor

References

1. Goff D, et al. Discovery of dual Axl/VEGF-R2 inhibitors as potential anti-angiogenic and anti-metastatic drugs for cancer chemotherapy. Bioorg Med Chem Lett. 2017 Aug 15; 27(16):3766-3771.