TargetMol

PF-06250112

Product Code:
 
TAR-T12673L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

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CodeSizePrice
TAR-T12673L-5mg5mg£1,091.00
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Quantity:
TAR-T12673L-50mg50mg£2,143.00
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Quantity:
TAR-T12673L-100mg100mg£2,801.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
PF-06250112 is an effective and highly selective BTK inhibitor (IC50: 0.5 nM. PF-06250112 displays an inhibitory effect toward BMX nonreceptor tyrosine kinase and TEC (IC50s: 0.9 nM and 1.2 nM, respectively).
CAS:
1609465-89-5
Formula:
C22H20F2N6O2
Molecular Weight:
438.439
Pathway:
Tyrosine Kinase/Adaptors; Angiogenesis
Purity:
0.98
SMILES:
NC(=O)c1c(N)n(nc1-c1ccc(Oc2ccc(F)cc2F)cc1)[C@H]1CCCN(C1)C#N
Target:
BTK

References

1. Rankin AL, et al. Selective inhibition of BTK prevents murine lupus and antibody-mediated glomerulonephritis. J Immunol. 2013 Nov 1;191(9):4540-50.