TargetMol

RBN-2397

Product Code:
 
TAR-T12695
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12695-1mg1mg£205.00
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TAR-T12695-5mg5mg£405.00
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TAR-T12695-1mL1 mL * 10 mM (in DMSO)£438.00
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TAR-T12695-10mg10mg£567.00
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TAR-T12695-25mg25mg£862.00
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TAR-T12695-50mg50mg£1,139.00
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Quantity:
TAR-T12695-100mg100mg£1,508.00
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Quantity:
TAR-T12695-500mg500mg£2,954.00
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Quantity:
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Further Information

Bioactivity:
RBN-2397 is a potent, selective and orally active accross species NAD+ competitive PARP7 inhibitor with IC50 less than 3 nM.
CAS:
2381037-82-5
Formula:
C20H23F6N7O3
Molecular Weight:
523.44
Pathway:
DNA Damage/DNA Repair; Chromatin/Epigenetic
Purity:
0.9996
SMILES:
C[C@@H](COCCC(=O)N1CCN(CC1)c1ncc(cn1)C(F)(F)F)Nc1cn[nH]c(=O)c1C(F)(F)F
Target:
PARP

References

2. Melissa Vasbinder, et al. RBN-2397: A First-in-Class PARP7 Inhibitor Targeting a Newly Discovered Cancer Vulnerability in Stress-Signaling Pathways.