TargetMol

Retro-2 cycl

Product Code:
 
TAR-T12711
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12711-5mg5mg£108.00
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TAR-T12711-1mL1 mL * 10 mM (in DMSO)£112.00
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TAR-T12711-10mg10mg£128.00
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TAR-T12711-25mg25mg£177.00
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TAR-T12711-50mg50mg£262.00
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TAR-T12711-100mg100mg£414.00
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Quantity:
TAR-T12711-200mg200mg£536.00
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This product comes from: United States.
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Further Information

Bioactivity:
Retro-2 cycl is an antiviral agent and a selective inhibitor of retrograde protein trafficking mediated by syntaxin-5 at the interface. Retro-2 cycl inhibits JCPyV(IC50s: 54 μM) and HPV16 pseudovirus(IC50s: 160 μM).
CAS:
1429192-00-6
Formula:
C19H16N2OS
Molecular Weight:
320.41
Pathway:
Microbiology/Virology
Purity:
0.9882
SMILES:
Cc1ccc(s1)C1Nc2ccccc2C(=O)N1c1ccccc1
Target:
Virus Protease

References

1. Carney DW, et al. Structural optimization of a retrograde trafficking inhibitor that protects cells from infections by human polyoma- and papillomaviruses. Bioorg Med Chem. 2014 Sep 1;22(17):4836-47.