TargetMol

(RS)-PPG

Product Code:
 
TAR-T12772
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12772-5mg5mg£850.00
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Quantity:
TAR-T12772-50mg50mg£1,661.00
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Quantity:
TAR-T12772-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
(RS)-PPG is a potent and selective group III mGluRs agonist(EC50s of 5.2 μM, 4.7 μM, 185 μM, and 0.2 μM for hmGluR4a, hmGluR6, hmGluR7b, and hmGluR8a, respectively),with neuroprotective and anticonvulsive activity.
CAS:
120667-15-4
Formula:
C8H10NO5P
Molecular Weight:
231.144
Purity:
0.98
SMILES:
NC(C(O)=O)c1ccc(cc1)P(O)(O)=O

References

1. Gasparini F, et al. (R,S)-4-phosphonophenylglycine, a potent and selective group III metabotropic glutamate receptor agonist, is anticonvulsive and neuroprotective in vivo. J Pharmacol Exp Ther. 1999 Jun;289(3):1678-87. 2. Zhao L, et al. Activation of group III metabotropic glutamate receptor reduces intracellular calcium in beta-amyloid peptide [31-35]-treated cortical neurons. Neurotox Res. 2009 Aug;16(2):174-83.