TargetMol

RTI-13951-33 hydrochloride

Product Code:
 
TAR-T12778
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T12778-25mg25mg£1,163.00
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TAR-T12778-50mg50mg£1,902.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
RTI-13951-33 hydrochloride is a potent, selective, and brain-penetrant agonist of GPR88(EC50 of 25 nM in GPR88 cAMP functional assay). It reduces alcohol reinforcement and intake behaviors in rats.
CAS:
T12778
Formula:
C28H35Cl2N3O3
Molecular Weight:
532.5
Purity:
0.98
SMILES:
COCC1=CC=C(C2=CC=C(N(C[C@@H](N)[C@@H](C)OC)C([C@H]3[C@H](C4=CC=CC=N4)C3)=O)C=C2)C=C1.Cl.Cl

References

1. Jin C, et al. Discovery of a Potent, Selective, and Brain-Penetrant Small Molecule that Activates the Orphan Receptor GPR88 and Reduces Alcohol Intake. J Med Chem. 2018 Aug 9;61(15):6748-6758.