TargetMol

RWJ 63556

Product Code:
 
TAR-T12784
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12784-1mg1mg£340.00
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TAR-T12784-5mg5mg£606.00
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TAR-T12784-1mL1 mL * 10 mM (in DMSO)£619.00
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TAR-T12784-10mg10mg£970.00
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TAR-T12784-25mg25mg£1,412.00
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TAR-T12784-50mg50mg£1,878.00
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Quantity:
TAR-T12784-100mg100mg£2,456.00
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This product comes from: United States.
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Further Information

Bioactivity:
RWJ 63556 is an orally active inhibitor of COX-2 selective/5-lipoxygenase, shows anti-inflammatory activities.
CAS:
190967-35-2
Formula:
C11H10FNO3S2
Molecular Weight:
287.33
Pathway:
Immunology/Inflammation; Neuroscience; Metabolism
Purity:
0.9891
SMILES:
O=S(=O)(NC=1SC(OC2=CC=C(F)C=C2)=CC1)C
Target:
Lipoxygenase; COX

References

1. Kirchner T, et al. Evaluation of the antiinflammatory activity of a dual cyclooxygenase-2 selective/5-lipoxygenase inhibitor, RWJ 63556, in a canine model of inflammation. J Pharmacol Exp Ther. 1997 Aug;282(2):1094-101. 2. Le Filliatre G, et al. Cyclo-oxygenase and lipoxygenase pathways in mast cell dependent-neurogenic inflammation induced by electrical stimulation of the rat saphenous nerve. Br J Pharmacol. 2001 Apr;132(7):1581-9.