TargetMol

SCH 42495 racemate

Product Code:
 
TAR-T12866
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12866-5mg5mg£850.00
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Quantity:
TAR-T12866-50mg50mg£1,661.00
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Quantity:
TAR-T12866-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
SCH 42495 racemate is the racemate of SCH 42495. SCH 42495 is an orally active neutral inhibitor of metalloendopeptidase (NEP), with antihypertensive effect.
CAS:
145841-10-7
Formula:
C20H29NO4S2
Molecular Weight:
411.58
Purity:
0.98
SMILES:
CCOC(=O)[C@H](CCSC)NC(=O)C(CSC(C)=O)Cc1ccccc1C

References

1. Watkins RW, et al. Atrial natriuretic factor potentiating and hemodynamic effects of SCH 42495, a new, neutral metalloendopeptidase inhibitor. Am J Hypertens. 1993 May;6(5 Pt 1):357-68. 2. Thompson JS, et al. Effects of the neutral endopeptidase inhibitor, SCH 42495, on the cardiovascular remodelling secondary to chronic hypoxia in rats. Clin Sci (Lond). 1994 Jul;87(1):109-14.