TargetMol

Synucleozid hydrochloride (502139-01-7 free base)

Product Code:
 
TAR-T13049L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13049L-5mg5mg£320.00
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TAR-T13049L-10mg10mg£461.00
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TAR-T13049L-50mg50mg£1,168.00
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TAR-T13049L-100mg100mg£2,051.00
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This product comes from: United States.
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Further Information

Bioactivity:
Synucleozid hydrochloride is a potent the SNCA mRNA inhibitor that encodes α-synuclein protein (IC50=1.5 μM), has the potential for the investigation of Parkinson?s disease.
CAS:
T13049L
Formula:
C22H21ClN6
Molecular Weight:
404.9
Purity:
0.98
SMILES:
N=C(C1=CC2=C(C=C1)C=C(C3=CC=C(NC4=CC=C(C(N)=N)C=C4)C=C3)N2)N.Cl

References

1. Zhang P, et al. Translation of the intrinsically disordered protein ?-synuclein is inhibited by a small molecule targeting its structured mRNA.Proc Natl Acad Sci U S A. 2020 Jan 21;117(3):1457-1467.