TargetMol

TL02-59 dihydrochloride

Product Code:
 
TAR-T13186L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13186L-5mg5mg£850.00
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Quantity:
TAR-T13186L-50mg50mg£1,661.00
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Quantity:
TAR-T13186L-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
TL02-59 dihydrochloride is an orally active inhibitor of Src-family kinase Fgr (IC50: 0.03 nM).
CAS:
2415263-06-6
Formula:
C32H36Cl2F3N5O4
Molecular Weight:
682.57
Pathway:
Angiogenesis; Tyrosine Kinase/Adaptors
Purity:
0.98
SMILES:
Cl.Cl.CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(Oc4ncnc5cc(OC)c(OC)cc45)c3)cc2C(F)(F)F)CC1
Target:
Src

References

1. Weir MC, et al. Selective Inhibition of the Myeloid Src-Family Kinase Fgr Potently Suppresses AML Cell Growth in Vitro and in Vivo. ACS Chem Biol. 2018 Jun 15;13(6):1551-1559.