TargetMol

UK-101

Product Code:
 
TAR-T13247
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13247-1mg1mg£400.00
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Quantity:
TAR-T13247-5mg5mg£844.00
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Quantity:
TAR-T13247-10mg10mg£1,107.00
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Quantity:
TAR-T13247-25mg25mg£1,564.00
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Quantity:
TAR-T13247-50mg50mg£1,982.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
UK-101 is a potent and selective inhibitor of immunoproteasome β1i (LMP2) (IC50: 104 nM), and induces cell apoptosis and can be used for prostate cancer.
CAS:
1000313-40-5
Formula:
C25H48N2O5Si
Molecular Weight:
484.753
Pathway:
Proteases/Proteasome|Ubiquitination
Purity:
0.98
SMILES:
CCCCCCC(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(CO[Si](C)(C)C(C)(C)C)CO1
Target:
Proteasome

References

1. Wehenkel M, et al. A selective inhibitor of the immunoproteasome subunit LMP2 induces apoptosis in PC-3 cells and suppresses tumour growth in nude mice. Br J Cancer.?2012?Jun 26;107(1):53-62.