TargetMol

UPF-648 sodium salt

Product Code:
 
TAR-T13258
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13258-5mg5mg£850.00
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Quantity:
TAR-T13258-50mg50mg£1,661.00
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Quantity:
TAR-T13258-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
UPF-648 sodium salt is an inhibitor of kynurenine 3-monooxygenase (KMO) and exhibits highly active at 1 uM (81 ? 10% KMO inhibition).
CAS:
1465017-87-1
Formula:
C11H7Cl2NaO3
Molecular Weight:
281.06
Purity:
0.98
SMILES:
[Na+].[O-]C(=O)C1CC1C(=O)c1ccc(Cl)c(Cl)c1

References

1. Amori L, et al. On the relationship between the two branches of the kynurenine pathway in the rat brain in vivo. J Neurochem. 2009 Apr;109(2):316-25. 2. Ceresoli-Borroni G, et al. Perinatal kynurenine 3-hydroxylase inhibition in rodents: pathophysiological implications. J Neurosci Res. 2007 Mar;85(4):845-54. 3. Amaral M, et al. Structural basis of kynurenine 3-monooxygenase inhibition. Nature. 2013 Apr 18;496(7445):382-5.