TargetMol

VU6005806

Product Code:
 
TAR-T13322
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13322-5mg5mg£1,251.00
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TAR-T13322-50mg50mg£2,464.00
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Quantity:
TAR-T13322-100mg100mg£3,283.00
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This product comes from: United States.
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Further Information

Bioactivity:
VU6005806 is a potent positive allosteric modulator (PAM) of muscarinic acetylcholine receptor subtype 4 (M4) (EC50s: 94 nM, 28 nM, 87 nM, and 68 nM for human, rat, dog, and cyno M4, respectively), and used in the study of neuropsychiatric disorders.
CAS:
2180914-37-6
Formula:
C17H16F3N7O2S
Molecular Weight:
439.42
Purity:
0.98
SMILES:
COc1nnc2sc(C(=O)NC3CN(C3)c3ncc(cn3)C(F)(F)F)c(N)c2c1C

References

1. Engers DW, et al. VU6005806/AZN-00016130, an advanced M4 positive allosteric modulator (PAM) profiled as a potential preclinical development candidate. Bioorg Med Chem Lett. 2019 Jul 15;29(14):1714-1718.