TargetMol

Wf-516

Product Code:
 
TAR-T13339
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13339-5mg5mg£1,010.00
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TAR-T13339-50mg50mg£1,982.00
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TAR-T13339-100mg100mg£2,560.00
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This product comes from: United States.
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Further Information

Bioactivity:
Wf-516 is a 5-HT reuptake inhibitor (Kis: 5 nM and 40 nM for 5-HT1A receptor and 5-HT2A receptor in humans, respectively), and with potent antidepressant activity.
CAS:
310392-94-0
Formula:
C25H25Cl2N3O4
Molecular Weight:
502.39
Pathway:
Neuroscience; GPCR/G Protein
Purity:
0.98
SMILES:
Cc1nnc(o1)-c1cc2c(OC[C@@H](O)CN3CCC(CC3)c3ccc(Cl)c(Cl)c3)cccc2o1
Target:
5-HT Receptor

References

1. El Mansari M, et al. In vivo electrophysiological assessment of the putative antidepressant Wf-516 in the rat raphe dorsalis, locus coeruleus and hippocampus. Naunyn Schmiedebergs Arch Pharmacol. 2008 Jan;376(5):351-61. Epub 2007 Nov 30. 2. Saijo T, et al. Presynaptic selectivity of a ligand for serotonin 1A receptors revealed by in vivo PET assays of rat brain. PLoS One. 2012;7(8):e42589.