TargetMol

AZ7550 Mesylate (1421373-99-0 free base)

Product Code:
 
TAR-T13564L2
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13564L2-100mg100mgEnquire
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TAR-T13564L2-50mg50mgEnquire
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TAR-T13564L2-5mg5mg£271.00
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TAR-T13564L2-10mg10mg£384.00
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This product comes from: United States.
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Further Information

Bioactivity:
AZ7550 hydrochloride, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).
CAS:
T13564L2
Formula:
C30H43N7O11S3
Molecular Weight:
773.9
Pathway:
MAPK
Purity:
0.98
SMILES:
CN1C=C(C2=NC(NC3=CC(NC(C=C)=O)=C(N(CCNC)C)C=C3OC)=NC=C2)C4=CC=CC=C41.O=S(O)(C)=O.O=S(O)(C)=O.O=S(O)(C)=O
Target:
MLK

References

1. Finlay MR, et al. Discovery of a potent and selective EGFR inhibitor (AZD9291) of both sensitizing and T790M resistance mutations that spares the wild type form of the receptor. J Med Chem. 2014 Oct 23;57(20):8249-67.