TargetMol

Cercosporin

Product Code:
 
TAR-T13605
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13605-5mg5mg£351.00
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Further Information

Bioactivity:
Cercosporin is produced by a plant pathogen, Cercosporakikuchii, and the elsinochromes. Cercosporin is a potent photosensitizer with a short activation wavelength. Cercosporin contains the perylene quinone structural features necessary for PKC activity (IC50: 0.6-1.3 μM).
CAS:
35082-49-6
Formula:
C29H26O10
Molecular Weight:
534.517
Pathway:
Chromatin/Epigenetic; Cytoskeletal Signaling
Purity:
0.98
SMILES:
COc1c(O)c2c3c(c1CC(C)O)c1c(CC(C)O)c(OC)c(=O)c4c(O)cc5OCOc(cc2=O)c3c5c14
Target:
PKC

References

1. Mastrangelopoulou M, et al. Cytotoxic and Photocytotoxic Effects of Cercosporin on Human Tumor Cell Lines. Photochem Photobiol. 2019 Jan;95(1):387-396. 2. Morgan BJ, et al. Design, synthesis, and investigation of protein kinase C inhibitors: total syntheses of (+)-calphostin D, (+)-phleichrome, cercosporin, and new photoactive perylenequinones. J Am Chem Soc. 2009 Jul 8;131(26):9413-25.