TargetMol

DSP-4 hydrochloride

Product Code:
 
TAR-T13664
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13664-5mg5mg£107.00
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TAR-T13664-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T13664-10mg10mg£122.00
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TAR-T13664-50mg50mg£201.00
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TAR-T13664-100mg100mg£271.00
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TAR-T13664-200mg200mg£371.00
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Further Information

Bioactivity:
DSP-4 hydrochloride (Neurotoxin DSP 4 hydrochloride) can be used for the temporary selective degradation of the central and peripheral noradrenergic neurons, mainly those from the locus coeruleus (LC). is a highly selective neurotoxin and readily passes the blood-brain barrier with neurotoxic effects on noradrenergic neurons of adult and developing rats,
CAS:
40616-75-9
Formula:
C11H16BrCl2N
Molecular Weight:
313.06
Purity:
0.9991
SMILES:
Cl.CCN(CCCl)Cc1ccccc1Br

References

1. Hormigo S, et al. The selective neurotoxin DSP-4 impairs the noradrenergic projections from the locus coeruleus to the inferior colliculus in rats. Front Neural Circuits. 2012 Jun 28;6:41. 2. Jaim-Etcheverry G, et al. DSP-4: a novel compound with neurotoxic effects on noradrenergic neurons of adult and developing rats. Brain Res. 1980 Apr 28;188(2):513-23.