TargetMol

GLPG-3221

Product Code:
 
TAR-T13704
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13704-5mg5mg£850.00
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TAR-T13704-50mg50mg£1,661.00
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Quantity:
TAR-T13704-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
GLPG-3221 can be uesd for the treatment of cystic fibrosis.GLPG-3221 is a potent, orally active corrector of CFTR (cystic fibrosis transmembrane conductance regulator), with an EC50 of 105 nM.
CAS:
2222264-64-2
Formula:
C30H37F3N2O6
Molecular Weight:
578.629
Purity:
0.98
SMILES:
COc1ncc(cc1CO[C@@H]1[C@@H](N([C@@H]([C@H]1C(C)(C)C)C(O)=O)C(=O)[C@@H]1CCCCO1)c1ccccc1C)C(F)(F)F

References

1. Scanio MJC, et al.Discovery?of?ABBV/GLPG-3221, a?Potent?Corrector?of?CFTR?for the Treatment of Cystic Fibrosis.ACS Med Chem Lett.?2019 Oct 31;10(11):1543-1548.