TargetMol

TL13-112

Product Code:
 
TAR-T13929
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

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CodeSizePrice
TAR-T13929-5mg5mg£324.00
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This product comes from: United States.
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Further Information

Bioactivity:
TL13-112 is a selective degrader of ALK-PROTAC and inhibits ALK activity (IC50: 0.14 nM).
CAS:
2229037-19-6
Formula:
C49H60ClN9O10S
Molecular Weight:
1002.58
Purity:
0.98
SMILES:
CC(C)Oc1cc(C2CCN(CCOCCOCCNC(=O)CNc3cccc4C(=O)N(C5CCC(=O)NC5=O)C(=O)c34)CC2)c(C)cc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1

References

1. Powell CE, et al. Chemically Induced Degradation of Anaplastic Lymphoma Kinase (ALK).J Med Chem.?2018?May 10;61(9):4249-4255.