TargetMol

2,2,5,7,8-Pentamethyl-6-Chromanol

Product Code:
 
TAR-T14008
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14008-100mg100mg£103.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T14008-1mL1 mL * 10 mM (in DMSO)£107.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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Further Information

Bioactivity:
2,2,5,7,8-Pentamethyl-6-Chromanol is the anti-oxidant moiety of vitamin E (α-tocopherol), which has potent androgen receptor (AR) signaling modulation and anti-cancer activity against prostate cancer cell lines.
CAS:
950-99-2
Formula:
C14H20O2
Molecular Weight:
220.312
Pathway:
Endocrinology/Hormones
Purity:
0.993
SMILES:
Cc1c(C)c2OC(C)(C)CCc2c(C)c1O
Target:
Androgen Receptor

References

1. Kyriakopoulos CE, et al. A multicenter phase 1/2a dose-escalation study of the antioxidant moiety of vitamin E 2,2,5,7,8-pentamethyl-6-chromanol (APC-100) in men with advanced prostate cancer. Invest New Drugs. 2016 Apr;34(2):225-30.