TargetMol

Agaric acid

Product Code:
 
TAR-T14140
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T14140-25mg25mg£103.00
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TAR-T14140-1mL1 mL * 10 mM (in DMSO)£107.00
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TAR-T14140-50mg50mg£124.00
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TAR-T14140-100mg100mg£149.00
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This product comes from: United States.
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Further Information

Bioactivity:
Agaricic acid is an adenine nucleotide translocase antagonist.It is obtained from various plants of the fungous tribe, i.e. Polyporus officinalis and Polyporus igniarius. Agaric acid induces mitochondrial permeability transition through its interaction with the adenine nucleotide translocase. Agaric acid promotes efflux of accumulated Ca 2+, collapse of transmembrane potential, and mitochondrial swelling. Agaric acid is used to regulate lipid metabolism.
CAS:
666-99-9
Formula:
C22H40O7
Molecular Weight:
416.555
Pathway:
Neuroscience; Metabolism
Purity:
0.98
SMILES:
CCCCCCCCCCCCCCCCC(C(O)=O)C(O)(CC(O)=O)C(O)=O
Target:
Mitochondrial Metabolism; AChR

References

1. Garc?a N, et al. Agaric acid induces mitochondrial permeability transition through its interaction with the adenine nucleotide translocase. Its dependence on membrane fluidity. Mitochondrion. 2005 Aug;5(4):272-81. 2. Edmundo Ch?vez, Buelna-Chontal M , Arturo Mac?as-L?pez, et al. Interaction of Agaric Acid with the Adenine Nucleotide Translocase Induces Mitochondrial Oxidative Stress[J]. Biochemistry Research International, 2020, 2020(3):1-8.