TargetMol

Alniditan

Product Code:
 
TAR-T14190
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14190-5mg5mg£850.00
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TAR-T14190-50mg50mg£1,661.00
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Quantity:
TAR-T14190-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Alniditan is a receptors agonist of 5-HT1B/1D in HEK 293 cells (IC50: 1.7 and 1.3 nM). For 5-HT1B/1D receptors, the pKi values are 8.96 and 9.40, respectively.
CAS:
152317-89-0
Formula:
C17H26N4O
Molecular Weight:
302.422
Pathway:
Neuroscience; GPCR/G Protein
Purity:
0.98
SMILES:
C(CNC[C@H]1CCc2ccccc2O1)CNC1=NCCCN1
Target:
5-HT Receptor

References

1. Limmroth V, et al. Effects of alniditan on neurogenic oedema in the rat dura mater and on contraction of rat basilar artery. Eur J Pharmacol. 1999 Oct 8;382(2):103-9. 2. De Vries P, et al. The antimigraine agent alniditan selectively constricts porcine carotid arteriovenous anastomoses via 5-HT1B/1D receptors. Eur J Pharmacol. 1998 Jun 19;351(2):193-201. 3. Lesage AS, et al. Agonistic properties of alniditan, sumatriptan and dihydroergotamine on human 5-HT1B and 5-HT1D receptors expressed in various mammalian cell lines. Br J Pharmacol. 1998 Apr;123(8):1655-65.