TargetMol

AM-8735

Product Code:
 
TAR-T14203
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14203-5mg5mg£1,010.00
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TAR-T14203-50mg50mg£1,982.00
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Quantity:
TAR-T14203-100mg100mg£2,560.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
AM-8735 is an inhibitor of MDM2 ( IC50: 25 nM).
CAS:
1429386-01-5
Formula:
C27H31Cl2NO6S
Molecular Weight:
568.51
Pathway:
Apoptosis
Purity:
0.98
SMILES:
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1[C@@H]([C@H](O[C@H](CC(O)=O)C1=O)c1cccc(Cl)c1)c1ccc(Cl)cc1
Target:
Mdm2

References

1. Gonzalez AZ, et al. Selective and potent morpholinone inhibitors of the MDM2-p53 protein-protein interaction. J Med Chem. 2014 Mar 27;57(6):2472-88.