TargetMol

BMS-248360

Product Code:
 
TAR-T14672
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14672-5mg5mg£1,492.00
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TAR-T14672-50mg50mg£2,946.00
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Quantity:
TAR-T14672-100mg100mg£4,006.00
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This product comes from: United States.
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Further Information

Bioactivity:
BMS-248360 is a potent and orally active dual antagonist of both angiotensin II receptor (AT1) and endothelin A (ETA) receptor. With Kis of 10 nM and 1.9 nM for hAT1 and hETA receptor, respectively. BMS-248360 shows hypertensive effects[1].
CAS:
254737-87-6
Formula:
C36H45N5O5S
Molecular Weight:
659.85
Purity:
0.98
SMILES:
CCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(c(CN2CCC(C)(C)C2=O)c1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C

References

1. Murugesan N, et al. Discovery of N-isoxazolyl biphenylsulfonamides as potent dual angiotensin II and endothelin A receptor antagonists. J Med Chem. 2002 Aug 29;45(18):3829-35.