TargetMol

BRD9185

Product Code:
 
TAR-T14780
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14780-5mg5mg£1,167.00
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Further Information

Bioactivity:
BRD9185 is an inhibitor of Dihydroorotate dehydrogenase (DHODH) with an EC50 of 16 nM against multidrug-resistant blood-stage parasites in vitro.
CAS:
2057420-29-6
Formula:
C23H21F6N3O2
Molecular Weight:
485.43
Pathway:
Metabolism
Purity:
0.98
SMILES:
CCCNC(=O)N1[C@H](CO)[C@H]([C@H]1C#N)c1ccc(cc1)-c1ccc(c(c1)C(F)(F)F)C(F)(F)F
Target:
Dehydrogenase

References

1. Maetani M, et al. Discovery of Antimalarial Azetidine-2-carbonitriles That Inhibit P. falciparum Dihydroorotate Dehydrogenase. ACS Med Chem Lett. 2017 Feb 27;8(4):438-442.