TargetMol

CI 972 anhydrous

Product Code:
 
TAR-T14964
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14964-5mg5mg£1,010.00
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TAR-T14964-50mg50mg£1,982.00
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Quantity:
TAR-T14964-100mg100mg£2,560.00
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This product comes from: United States.
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Further Information

Bioactivity:
CI 972 anhydrous is an inhibitor of purine nucleoside phosphorylase (PNP) (Ki: 0.83 μM) used as a T cell-selective immunosuppressive agent.
CAS:
115787-68-3
Formula:
C11H12ClN5OS
Molecular Weight:
297.76
Purity:
0.98
SMILES:
Cl.Nc1[nH]c2c([nH]c(N)nc2=O)c1Cc1ccsc1

References

1. Gilbertsen RB, et al. Biochemical and pharmacological properties of CI-972, a novel 9-deazaguanine analog purine nucleoside phosphorylase (PNP) inhibitor. Adv Exp Med Biol. 1991;309A:41-4. 2. Gilbertsen RB,et al. Selective in vitro inhibition of human MOLT-4 T lymphoblasts by the novel purine nucleoside phosphorylase inhibitor, CI-972. Biochem Biophys Res Commun. 1991 Aug 15;178(3):1351-8.